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Azathioprine e Malattia del fegato

Risultato del controllo d'interazione tra il farmaco Azathioprine e la malattia Malattia del fegato su sicurezza in caso d'uso simultaneo.

Risultato di controllo:

Azathioprine <> Malattia del fegato

Rilevanza: 23.07.2019 Recensore: P.M. Shkutko, dott., in

Durante il controllo d'interazione, secondo le fonti autorevoli Drugs.com, Rxlist.com, Webmd.com, Medscape.com sono trovate le controindicazioni o gli effetti collaterali che possono danneggiare oppure intensificare l’effetto negativo in caso d'uso del farmaco in presenza di questa malattia concomitante.

Consumatore:

L'azatioprina è metabolicamente convertito farmacologicamente attive 6-mercaptopurina (6-MP). Conversione di 6-MP e il metabolismo di 6-MP può essere ridotta nei pazienti con malattia epatica. La terapia con azatioprina deve essere somministrato con cautela in pazienti con malattia epatica. Monitoraggio della funzione epatica è raccomandato in questi pazienti.

Fonte

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