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Activase e Rischi di sanguinamento

Risultato del controllo d'interazione tra il farmaco Activase e la malattia Rischi di sanguinamento su sicurezza in caso d'uso simultaneo.

Risultato di controllo:

Activase <> Rischi di sanguinamento

Rilevanza: 23.07.2019 Recensore: P.M. Shkutko, dott., in

Durante il controllo d'interazione, secondo le fonti autorevoli Drugs.com, Rxlist.com, Webmd.com, Medscape.com sono trovate le controindicazioni o gli effetti collaterali che possono danneggiare oppure intensificare l’effetto negativo in caso d'uso del farmaco in presenza di questa malattia concomitante.

Consumatore:

L'uso di trombolitici è controindicato in pazienti con un attivo di spurgo (interno), trauma/chirurgia (recenti CPR/intracranica/intraspinale intervento chirurgico entro 2 mesi), diatesi emorragica, storia di malattie cerebrovascolari (CV) incidente, intracranica difetto (aneurismi, malformazioni artero-venose, neoplasia), o gravi incontrollata ipertensione arteriosa (SBP>180/DBP>110). Tra rischio e beneficio deve essere attentamente valutata in base alle seguenti condizioni e terapia trombolitica somministrato con cautela in pazienti con recente (10 giorni) gravi GI bleed o recente (10 giorni) procedura chirurgica (bypass coronarico innesto, ostetrica consegna, biopsia d'organo, puntura di noncompressible di nave), cuore a sinistra trombo, endocardite batterica subacuta, emostatici difetto, CV malattia diabetica retinopatia emorragica, o la gravidanza. Il monitoraggio clinico di cellule ematopoietiche, sanguinamento e coagulazione funzioni è raccomandato prima di iniziare la terapia trombolitica. Misure di attività fibrinolitica e/o la coagulazione funzioni durante l'infusione non correlare con efficacia o rischio di sanguinamento.

Fonte

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